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(530) 752-8570 FAX: (530) 752-8885 e-mail: dgsmith@ucdavis.edu |
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(530) 752-8570 FAX: (530) 752-8885 e-mail: dgsmith@ucdavis.edu |
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Research Emphasis/Objectives:
Identify and characterize short tandem repeat (STR) polymorphisms to study the effectiveness of alternate genetic management strategies and the effects of social and demographic factors on the population/genetic structure of captive groups of primates; identify marker loci for genes that influence susceptibility to specific infections; employ both ancient and contemporary mitochondrial DNA and Y-chromosome haplotypes for studies of ancestor-descendant relationships.
Resources Provided:
All principal investigators of NIH-supported SPF breeding programs or their designees are eligible to submit samples of any species of macaque, baboon or other primate taxa for genetic marker analysis. We develop and apply PCR-amplified STR markers to identify parentage, calculate kinship and inbreeding coefficients, estimate parameters of genetic diversity, genetic subdivision and founder representation within the colony, and collaborate with principal investigators on colony management strategies and on research involving those data.
For Collaborators:
DNA samples (between 1 and 5 mls of whole blood or 1 mg of tissue) should be shipped overnight in dry ice to our laboratory. Pricing is negotiable, depending on resources. Acknowledgment should be given in all publications (including theses and dissertations) that result from our services, and two reprints should be donated to our laboratory.